Sydney Naturopath and Nutritionist
The term polycystic ovarian syndrome (PCOS) is a misleading name for what is essentially a multifaceted metabolic condition that has broad-ranging systemic effects, which impact hormonal and metabolic health. In fact, having polycystic ovaries is only part of the PCOS diagnosis.
Although most commonly associated with androgen excess, Polycystic Ovarian Syndrome (PCOS) is the outcome of a systemic metabolic and reproductive hormone dysregulation. So, what is PCOS and how can we restore hormonal and metabolic health once it has been diagnosed?
PCOS affects circa 12-20% of Australian women of reproductive age, and is more common in women who are overweight or of indigenous background. The prevalence of PCOS has been steadily increasing over the last decade1.
It is also the most common cause of anovulatory infertility in Australian women. Ovulation is the essential pre-qual to conception, which is why women with PCOS may have issues with fertility.
A diagnosis of PCOS comes as a shock to most women, and its potential to lead to fertility problems are legitimately cause for concern. Often, women are put on the contraceptive pill by their doctors, and told to come back when they want to have a baby.
On the other hand, natural medicine, along with dietary and lifestyle modifications, can address the causes of PCOS to achieve great results. With the right type of support, PCOS can be successfully managed, and symptoms can be completely reversed in some cases.
We all carry subtle genetic variations that may predispose us to certain conditions. In the case of PCOS, it appears that stress and poor diet can trigger genes that influence insulin signalling, hormone metabolism, and the production of androgens from the ovaries and adrenal glands.
Circa 80% of women with PCOS have some degree of insulin resistance. For this reason, insulin resistance is rightly the main focus on research and treatment. Insulin is a hormone that acts like a key, allowing glucose (sugar) from the blood stream to enter the cell, where it is used as fuel. In insulin resistance, cells do not readily open to insulin, forcing the pancreas to produce more and more insulin to try to get sugar out of the blood and into the cells. What this means is that we have excess sugar and insulin in the blood stream, but not enough sugar in the cell where it is actually needed. Hello fatigue (due to lack of cellular energy) and sugar cravings, despite high levels of sugar in the blood. Excess circulating insulin leads to weight gain, but it also overstimulates ovarian follicles, causing the appearance of polycystic ovaries. This overstimulation results in excess production of androgens, and disrupts the hypothalamic-pituitary-ovarian axis (signals from the brain to the ovaries), resulting in oligo/anovulation.
The development of insulin resistance relies of several factors, including diet, stress and inflammation.
A typical diet that would lead to insulin resistance is a high sugar, low fibre diet. That is, a diet that pertains refined carbohydrates, sugary foods and drinks, and inadequate vegetable intake. Some women may be more sensitive to a diet high in refined carbohydrates, due to individual genetic susceptibility.
Stress can play a significant role in PCOS development due to its ability to alter glucose metabolism, insulin sensitivity, and impact the production of adrenal hormones. In women, both the ovaries and adrenal glands produce hormones that act as androgens. In women who have been ‘burning the candle at both ends’ so to say, the adrenal glands start to produce higher levels of androgenic hormones, such as DHEA-S. In fact, chronically stressed women with PCOS may present with normal testosterone levels (the androgen secreted primarily from the ovaries), but elevated DHEA-S levels, which can be the cause of their male pattern hair loss, excessive facial or body hair, or acne.
Inflammation is an overlooked factor in PCOS. It is a double-edged sword that drives both insulin resistance and the production of androgens from polycystic ovaries. There are many causes of low-grade inflammation, but one of the most common is poor digestive function and dysbiosis. Dysbiosis is the imbalance of the billions of bacteria living in our guts. Causes of dysbiosis include a high sugar, high saturated fat diet, pesticides, food additives, medications such as antibiotics and the oral contraceptive pill, and stress. Dysbiosis may lead to increased intestinal permeability, whereby toxins or undigested food particles leak into the blood stream, causing chronic low-grade inflammation. Healthy bowel function is also imperative for hormone metabolism (as hormones are excreted via the bowels). Therefore, when gut symptoms are present, treating the gut is essentially the first step in treating PCOS.
Dietary intervention is the first line treatment in most PCOS cases. An anti-inflammatory diet, such as one which is high in plant foods, with moderate intake of fish, seafood, nuts and seeds to provide healthy fats and adequate protein, is the best way to improve insulin sensitivity, and support hormonal and gut health.
Exercise is an important feature in PCOS recovery, but must be tailored to the individual. For example, women with a typical picture of insulin resistant PCOS would benefit from a more intensive exercise protocol than women with elevated DHEA-S only (stress induced), who would get more benefit from a more restorative routine.
To support diet and lifestyle intervention, both nutritional and herbal medicines work exceptionally well in PCOS. Nutrients such as magnesium, chromium and alpha lipoic acid help to stabilise blood sugar levels. Nutraceuticals such as inositol and N-acetylcysteine have been shown to improve insulin sensitivity. Herbs such as Peony and Licorice have been used for centuries to support ovarian function, ovulation and the adrenal glands, while also reducing the production of androgens in the ovaries.
Book an appointment with Naturopath Liana Madera to uncover the root cause of your PCOS, and start experiencing the benefits of a natural cycle.
The journey to hormonal health is not always easy, but once you find your balance, you’ll have the key the lifelong female vitality.